CYBERMED LIFE - ORGANIC  & NATURAL LIVING

Dietary Modification - Wheat-Gluten Free

Lane-Hamilton syndrome: case report and review of the literature.

Written by CYBERMED LIFE NEWS
facebook Share on Facebook
Abstract Title:

Lane-Hamilton syndrome: case report and review of the literature.

Abstract Source:

Eur J Pediatr. 2011 Dec ;170(12):1597-602. Epub 2011 Sep 23. PMID: 21947219

Abstract Author(s):

Guy F M Hendrickx, Katia Somers, Yvan Vandenplas

Article Affiliation:

UZ kinderziekenhuis Brussel, Laarbeeklaan, 101, 1090 Brussel, Belgium. This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract:

We report a case of a three-and-a-half-year-old boy, who presented with poor general condition, stunted growth, had the presence of nail clubbing, persistent cough and frequent diarrhoea. Persistent iron deficiency anaemia without signs of haemolysis suggested Lane-Hamilton syndrome (LHS) which is or/is an extremely rare combination of idiopathic pulmonary haemosiderosis (IPH) and celiac disease (CD), although both diseases are immunologically mediated and the pathogenetic link between them is not clear. We have now 3 years of follow-up on gluten-free diet (GFD), resulting in a gradual recovery of the abnormal laboratory results in combination with an improving growth. Clinically, he is asymptomatic without any additional treatment. Our case illustrates that CD should be specifically looked for in patients with IPH, especially those in whom the severity of anaemia is disproportionate to the IPH symptoms. Both diseases may benefit from a GFD.


We use cookies on our website. Some of them are essential for the operation of the site, while others help us to improve this site and the user experience (tracking cookies). You can decide for yourself whether you want to allow cookies or not. Please note that if you reject them, you may not be able to use all the functionalities of the site.