Colon irrigation causes lymphocyte movement from gut-associated lymphatic tissues to peripheral blood.
Biomed Res. 2009 Oct;30(5):311-4. PMID: 19887728
It is well established that the intestine is an important site responsible for the local immune system. It is speculated that people suffering from constipation and carrying fecal residues in the intestine may have a decreased function of this immune system. In this study, colon irrigation, which is cleansing of the colon using a simple hydrotherapy instrument, was performed in 10 subjects with or without the disease. The number of leukocytes and their demarcation were then evaluated. The number and ratio of lymphocytes increased significantly after irrigation. This result suggested that colon irrigation might induce lymphocyte transmigration from gut-associated lymphatic tissues into the circulation, which may improve colon and immune system function.
Article Published Date : Oct 01, 2009
[Pseudocontinent perineal colostomy: an exceptional complication].
Pan Afr Med J. 2018;30:258
Authors: El Marouni A, Zerhouni A, Majdoub KH
Stoma prolapse is an exceptional and late complication of pseudocontinent perineal colostomy. Very rare cases have been described in the literature. We here report the case of a 75 year old patient with no particular past medical history as well as our therapeutic approach. The patient initially underwent surgery for non-metastatic rectal adenocarcinoma measuring 1 cm from the anal margin after radiochemotherapy. Laparoscopic abdominoperineal resection was performed with confection of a continent perineal colostomy. During follow up, clinical examination showed colon prolapse through the stoma orifice for which he was admitted to hospital for surgery. The complications of pseudocontinent perineal colostomy are mainly related to operative morbidity due to rectal resection (infections and perineal eventrations), to stoma complications (necrosis, prolapse, herniation). Stoma prolapse is an exceptional complication of continent perineal colostomy. Monitoring and patient education on irrigation technique are usually sufficient. Surgery is necessary in patients with bulky hardly reducible voluminous prolapse, embarrassing the patient and with weeping. Surgery is based on simple peristromal resection of the prolapsed segment. It has been reported that prolapsed segment grafting under simple sedation can be performed. Abdominoperineal resection is a mutilating procedure which is poorly perceived by patients. Pseudocontinent perineal colostomy is a simple safe and reproducible technique associated with a relatively low morbidity. Stoma prolapse is a rare and easily treated complication.
PMID: 30637043 [PubMed - in process]
Impact of a Novel Surgical Wound Protection Device on Observed versus Expected Surgical Site Infection Rates after Colectomy Using the National Surgical Quality Improvement Program Risk Calculator.
Surg Infect (Larchmt). 2019 Jan;20(1):35-38
Authors: Papaconstantinou HT, Birnbaum EH, Ricciardi R, Margolin DA, Moesinger RC, Lichliter WE, Thomas JS, Bergamaschi R
BACKGROUND: Surgical site infection (SSI) remains a persistent and morbid problem in colorectal surgery. A novel surgical device that combines barrier surgical wound protection and continuous surgical wound irrigation was evaluated in a cohort of elective colorectal surgery patients. A retrospective analysis was performed comparing rates of SSI observed in a prospective cohort study with the predicted rate of SSI using the American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) Risk Calculator.
PATIENTS AND METHODS: A prospective multi-center study of colectomy patients was conducted using a study device for surgical site retraction and protection, as well as irrigation of the incision. Patients were followed for 30 days after the surgical procedure to assess for SSI. After completion of the study, patients' characteristics were inserted into the ACS-NSQIP Risk Calculator to determine the predicted rate of SSI for the given patient population and compared with the observed rate in the study.
RESULTS: A total of 108 subjects were enrolled in the study. The observed rate of SSI in the prospective study using the novel device was 3.7% (4/108). The predicted rate of SSI in the same patient population utilizing the ACS-NSQIP Risk Calculator was estimated to be 9.5%. This demonstrated a 61% difference (3.7% vs. 9.5%, p = 0.04) in SSI from the NSQIP predicted rate with the use of the irrigating surgical wound protection and retraction device.
CONCLUSIONS: These data suggest the use of a novel surgical wound protection device seems to reduce the rate of SSIs in colorectal surgery.
PMID: 30234435 [PubMed - indexed for MEDLINE]