Cybermedlife - Therapeutic Actions Colon Irrigation

Colon irrigation causes lymphocyte movement from gut-associated lymphatic tissues to peripheral blood. 📎

Abstract Title: Colon irrigation causes lymphocyte movement from gut-associated lymphatic tissues to peripheral blood. Abstract Source: Biomed Res. 2009 Oct;30(5):311-4. PMID: 19887728 Abstract Author(s): Yoko Uchiyama-Tanaka Abstract: It is well established that the intestine is an important site responsible for the local immune system. It is speculated that people suffering from constipation and carrying fecal residues in the intestine may have a decreased function of this immune system. In this study, colon irrigation, which is cleansing of the colon using a simple hydrotherapy instrument, was performed in 10 subjects with or without the disease. The number of leukocytes and their demarcation were then evaluated. The number and ratio of lymphocytes increased significantly after irrigation. This result suggested that colon irrigation might induce lymphocyte transmigration from gut-associated lymphatic tissues into the circulation, which may improve colon and immune system function. Article Published Date : Oct 01, 2009
Therapeutic Actions Colon Irrigation

NCBI pubmed

Long-term results using a transanal irrigation system (Peristeen®) for treatment of stool incontinence in children with myelomeningocele.

Related Articles Long-term results using a transanal irrigation system (Peristeen®) for treatment of stool incontinence in children with myelomeningocele. J Pediatr Urol. 2018 Aug 28;: Authors: Alhazmi H, Trbay M, Alqarni N, Alyami F, Khatab A, Almannie R, Neel KF Abstract INTRODUCTION: Faecal incontinence due to constipation associated with myelomeningocele (MMC) is a frustrating problem. It could have a bad impact on patients and their families' quality of life. Conservative measures could be a starting point. In case of failure, Malone antegrade continence enema (MACE) is commonly considered. However, it is associated with higher complications. Peristeen transanal irrigation (TAI) depends on the injection of water into the colon through a rectal catheter with an inflatable balloon to promote a controlled evacuation of large quantities of faecal contents. Transanal irrigation could be an alternative in these patients to avoid surgery. OBJECTIVE: The objective of this study was to evaluate the long-term effectiveness and satisfaction of TAI management (Peristeen®, Coloplast, Denmark) in children with MMC who failed to respond to conservative measures for stool incontinence. STUDY DESIGN: All patients with MMC who did not respond to conservative measures for stool incontinence and were using TAI with the last follow-up 6 months before the end date were included. Data were collected retrospectively from January 2008 till January 2016. The data collected included the age of starting Peristeen, duration of using the Peristeen, acceptance and compliance of the patient's family with the TAI. Success was defined as stool continence. RESULTS: A total of 109 patients (55 males and 54 females) diagnosed as having MMC were started on TAI Peristeen. With a mean follow-up of 48 months (24-108), 101 patients (90.4%) achieved complete stool continence and 8 patients were considered failures. DISCUSSION: The study results are comparable with those of previously reported publications. The main limitation of Peristeen TAI is that it cannot be performed by the patient himself/herself. This may present a problem with later independence. CONCLUSION: Transanal irrigation with Peristeen® system is a safe and good alternative option for stool incontinence when other conservative measures fail. PMID: 30245057 [PubMed - as supplied by publisher]