Effectiveness of a noninvasive digital infrared thermal imaging system in the detection of breast cancer
Am J Surg. 2008 Oct;196(4):523-6. PMID: 18809055
Nimmi Arora, Diana Martins, Danielle Ruggerio, Eleni Tousimis, Alexander J Swistel, Michael P Osborne, Rache M Simmons
Department of Surgery, New York Presbyterian Hospital-Cornell, New York, NY, USA.
BACKGROUND: Digital infrared thermal imaging (DITI) has resurfaced in this era of modernized computer technology. Its role in the detection of breast cancer
METHODS: In this prospective clinical trial, 92 patients for whom a breast biopsy was recommended based on prior mammogram or ultrasound
underwent DITI. Three scores were generated: an overall risk score in the screening mode, a clinical score based on patient information, and a third assessment by artificial neural network.
RESULTS: Sixty of 94 biopsies were malignant and 34 were benign. DITI identified 58 of 60 malignancies, with 97% sensitivity, 44% specificity, and 82% negative predictive value depending on the mode used. Compared to an overall risk score of 0, a score of 3 or greater was significantly more likely to be associated with malignancy (30% vs 90%, P<.03).
CONCLUSION: DITI is a valuable adjunct to mammography and ultrasound
, especially in women with dense breast parenchyma.
Article Published Date : Oct 01, 2008