CYBERMED LIFE - ORGANIC  & NATURAL LIVING

Dermatitis

Dermatitis, also known as eczema, is a group of diseases that results in inflammation of the skin. These diseases are characterized by itchiness, red skin and a rash. In cases of short duration, there may be small blisters, while in long-term cases the skin may become thickened. The area of skin involved can vary from small to the entire body.

Dermatitis is a group of skin conditions that includes atopic dermatitis, allergic contact dermatitis, irritant contact dermatitis and stasis dermatitis. The exact cause of dermatitis is often unclear. Cases may involve a combination of irritation, allergy and poor venous return. The type of dermatitis is generally determined by the person's history and the location of the rash. For example, irritant dermatitis often occurs on the hands of people who frequently get them wet. Allergic contact dermatitis occurs upon exposure to an allergen, causing a hypersensitivity reaction in the skin.

Treatment of atopic dermatitis is typically with moisturizers and steroid creams. The steroid creams should generally be of mid- to high strength and used for less than two weeks at a time as side effects can occur. Antibiotics may be required if there are signs of skin infection. Contact dermatitis is typically treated by avoiding the allergen or irritant. Antihistamines may help with sleep and to decrease nighttime scratching.

Dermatitis was estimated to affect 245 million people globally in 2015. Atopic dermatitis is the most common type and generally starts in childhood. In the United States, it affects about 10–30% of people. Contact dermatitis is twice as common in females than males. Allergic contact dermatitis affects about 7% of people at some point in time. Irritant contact dermatitis is common, especially among people who do certain jobs; exact rates are unclear.

  • Dermatitis

  • Dermatitis

    Dermatitis, also known as eczema, is a group of diseases that results in inflammation of the skin. These diseases are characterized by itchiness, red skin and a rash. In cases of short duration, there may be small blisters, while in long-term cases the skin may become thickened. The area of skin involved can vary from small to the entire body.

  • Photobiomodulation therapy for the management of radiation-induced dermatitis : A single-institution experience of adjuvant radiotherapy in breast cancer patients after breast conserving surgery.

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    Abstract Title:

    Photobiomodulation therapy for the management of radiation-induced dermatitis : A single-institution experience of adjuvant radiotherapy in breast cancer patients after breast conserving surgery.

    Abstract Source:

    Strahlenther Onkol. 2017 Jun ;193(6):491-498. Epub 2017 Feb 27. PMID: 28243723

    Abstract Author(s):

    Iosif Strouthos, Georgios Chatzikonstantinou, Nikolaos Tselis, Dimitra Bon, Efstratios Karagiannis, Eleni Zoga, Konstantinos Ferentinos, Julia Maximenko, Vassiliki Nikolettou-Fischer, Nikolaos Zamboglou

    Article Affiliation:

    Iosif Strouthos

    Abstract:

    BACKGROUND:Radiation therapy (RT) comprises a key component in the treatment of breast cancer. Radiation-induced skin toxicity is the major adverse event experienced by patients; however, radiodermatitis (RD) prevention and management remains trivial. It is proven that photobiomodulation (PBM) therapy using light-emitting diode (LED) increases wound healing and depicts an anti-inflammatory effect. This single-institute study evaluates the beneficial role of PBM-LED in preventing/reducing RD during breast cancer RT.

    PATIENTS AND METHODS:Of 70 consecutively treated patients, 25 patients were treated with PBM-LED twice a week prior to adjuvant 3D conformal RT after breast-conserving surgery. RD was reported using Common Toxicity Criteria for Adverse Events Version 4.0 and pain intensity using a visual analog scale (VAS). For comparison, a control group (n = 45) received RT without PBM-LED. In addition, a "matched"group (n = 25) was generated from the control group based on propensity for potentially confounding variables.

    RESULTS:In the PBM group, 22 patients (88%) presented grade 1 and 3 (12%) grade 2 RD. In the control group, 25 patients (55.6%) developed grade 1 reactions, 18 patients (40%) grade 2, and 2 (4.4%) patients grade 3 RD. Concerning pain intensity, 15 patients (60%) of the PBM treatment arm reported no pain, 5 patients (20%) VAS 2, and 5 (20%) VAS 3. In the control group, 13 patients (28.9%) reported no pain, 2 (4.4%) VAS 1, 7 (15.6%) VAS 2, 9 patients (20%) reported VAS 3, 12 (26.7%) patients VAS 4, and 2 (4.4%) patients VAS 5.

    CONCLUSION:PBM-LED therapy applied prior to RT might be effective in decreasing the incidence and sequelae of radiation-induced skin toxicity in breast cancer patients treated with breast-conserving surgery.

  • Systemic Allergic Contact Dermatitis After Formaldehyde-Containing Influenza Vaccination.

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    Abstract Title:

    Systemic Allergic Contact Dermatitis After Formaldehyde-Containing Influenza Vaccination.

    Abstract Source:

    J Cutan Med Surg. 2015 Sep-Oct;19(5):504-6. Epub 2015 Apr 15. PMID: 25876644

    Abstract Author(s):

    L Alexandra Kuritzky, Melanie Pratt

    Article Affiliation:

    L Alexandra Kuritzky

    Abstract:

    BACKGROUND:Systemic contact dermatitis occurs when a patient sensitized to an allergen topically is systemically reexposed to the allergen and develops a cutaneous eruption.

    OBJECTIVE:To report the case of a 48-year-old male who developed explosive dermatitis following injection of a formaldehyde-containing influenza vaccine and was subsequently shown to be strongly positive to formaldehyde and formaldehyde-releasing allergens by patch testing, as well as to review the literature for similar cases.

    METHODS:A PubMed search was made using the following search terms: systemic contact dermatitis, formaldehyde, influenza, and vaccine.

    RESULTS:A review of the literature revealed 2 cases of systemic contact dermatitis from formaldehyde derived from aspartame and 1 case from a thimerosal-containing influenza vaccine. No cases caused by formaldehyde in influenza or other vaccines were found.

    CONCLUSION:This case highlights the importance of considering systemic allergic contact dermatitis in any patient presenting with dermatitis following injection of a formaldehyde-containing vaccine.

  • The Preventive Effect of Coffee Compounds on Dermatitis and Epidermal Pigmentation after Ultraviolet Irradiation in Mice. 📎

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    Abstract Title:

    The Preventive Effect of Coffee Compounds on Dermatitis and Epidermal Pigmentation after Ultraviolet Irradiation in Mice.

    Abstract Source:

    Skin Pharmacol Physiol. 2017 ;30(1):24-35. Epub 2017 Feb 3. PMID: 28152530

    Abstract Author(s):

    Yurika Yamate, Keiichi Hiramoto, Eisuke F Sato

    Article Affiliation:

    Yurika Yamate

    Abstract:

    BACKGROUND:Ultraviolet (UV) irradiation is well known to promote inflammation and pigmentation of skin. UVB mainly affects dermatitis and pigmentation. Coffee contains a number of polyphenols, such as caffeic acid (CA) and chlorogenic acid (CGA) but their in vivo bioactivity for photobiology remains unclear.

    METHODS:C57BL/6j male mice were irradiated with UVB (1.0 kJ/m2/day) for 3 days. Five days after the final session of UVB irradiation, the dorsal skin, ear epidermis, and blood samples were analyzed to investigate the inflammatory factors, melanogenesis factors and related hormones.

    RESULTS:After the oral administration of CA (100 mg/day) or CGA (100 mg/day) for 8 days, only CA was found to inhibit dermatitis and pigmentation. The pathway by which CA inhibits dermatitis is related to the mitogen-activated protein kinase (MAPK)/extracellular signal regulated kinase (ERK)1/2/cAMP response element binding protein (CREB) pathway. Otherwise, the pathway by which CA inhibits pigmentation is related to the activation of theβ-endorphin-μ-opioid receptor and suppresses the cAMP-microphthalmia-associated transcription factor (MITF) pathway.

    CONCLUSION:It is suggested that the oral administration of CA prevented dermatitis and pigmentation after UVB irradiation in mice.

  • The truth about phenoxyethanol

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    The truth about phenoxyethanol image

    It’s commonly used in cosmetics in place of parabens, but is this alternative preservative safe?

    What is it?
    Phenoxyethanol is a synthetic chemical widely used as a preservative in cosmetics and personal care products and as a fixative in perfumes. An oily, colorless liquid with antimicrobial activity, it can also be listed on the label as 2-phenoxyethanol, PhE, ethylene glycol monophenyl ether, rose ether or as Euxyl K® 400, which is mixture of phenoxyethanol and dibromodicyanobutane (also known as methyldibromo glutaronitrile). It appears to be increasingly used in place of parabens, which have been fingered as key chemicals of concern in recent years. But questions have been raised over the safety of phenoxyethanol too, and there's much debate online as to whether this alternative preservative should be applauded or avoided.

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