Cybermedlife - Therapeutic Actions Exercise Strenuous

Beyond recreational physical activity: examining occupational and household activity, transportation activity, and sedentary behavior in relation to postmenopausal breast cancer risk. 📎

Abstract Title: Beyond recreational physical activity: examining occupational and household activity, transportation activity, and sedentary behavior in relation to postmenopausal breast cancer risk. Abstract Source: Am J Public Health. 2010 Sep 23. Epub 2010 Sep 23. PMID: 20864719 Abstract Author(s): Stephanie M George, Melinda L Irwin, Charles E Matthews, Susan T Mayne, Mitchell H Gail, Steven C Moore, Demetrius Albanes, Rachel Ballard-Barbash, Albert R Hollenbeck, Arthur Schatzkin, Michael F Leitzmann Article Affiliation: National Cancer Institute, Yale School of Public Health. Abstract: Objectives. We prospectively examined nonrecreational physical activity and sedentary behavior in relation to breast cancer risk among 97039 postmenopausal women in the National Institutes of Health-AARP Diet and Health Study. Methods. We identified 2866 invasive and 570 in situ breast cancer cases recorded between 1996 and 2003 and used Cox proportional hazards regression to estimate multivariate relative risks (RRs) and 95% confidence intervals (CIs). Results. Routine activity during the day at work or at home that included heavy lifting or carrying versus mostly sitting was associated with reduced risk of invasive breast cancer (RR=0.62; 95% CI=0.42, 0.91; Ptrend=.024). Conclusions. Routine activity during the day at work or home may be related to reduced invasive breast cancer risk. Domains outside of recreation time may be attractive targets for increasing physical activity and reducing sedentary behavior among postmenopausal women. (Am J Public Health. Published online ahead of print September 23, 2010: e1-e8. doi:10.2105/AJPH.2009.180828). Note: RR=.62 = 38% relative risk reduction Article Published Date : Sep 23, 2010

Effects of beta-alanine supplementation and high-intensity interval training on endurance performance and body composition in men; a double-blind trial. 📎

Abstract Title: Effects of beta-alanine supplementation and high-intensity interval training on endurance performance and body composition in men; a double-blind trial. Abstract Source: J Int Soc Sports Nutr. 2009;6:5. Epub 2009 Feb 11. PMID: 19210788 Abstract Author(s): Abbie E Smith, Ashley A Walter, Jennifer L Graef, Kristina L Kendall, Jordan R Moon, Christopher M Lockwood, David H Fukuda, Travis W Beck, Joel T Cramer, Jeffrey R Stout Article Affiliation: Metabolic and Body Composition Laboratory, Department of Health and Exercise Science, University of Oklahoma, Norman, OK 73019, USA. This email address is being protected from spambots. You need JavaScript enabled to view it.. Abstract: ABSTRACT: BACKGROUND: Intermittent bouts of high-intensity exercise result in diminished stores of energy substrates, followed by an accumulation of metabolites, promoting chronic physiological adaptations. In addition, beta-alanine has been accepted has an effective physiological hydrogen ion (H+) buffer. Concurrent high-intensity interval training (HIIT) and beta-alanine supplementation may result in greater adaptations than HIIT alone. The purpose of the current study was to evaluate the effects of combining beta-alanine supplementation with high-intensity interval training (HIIT) on endurance performance and aerobic metabolism in recreationally active college-aged men. METHODS: Forty-six men (Age: 22.2 +/- 2.7 yrs; Ht: 178.1 +/- 7.4 cm; Wt: 78.7 +/- 11.9; VO2peak: 3.3 +/- 0.59 l.min-1) were assessed for peak O2 utilization (VO2peak), time to fatigue (VO2TTE), ventilatory threshold (VT), and total work done at 110% of pre-training VO2peak (TWD). In a double-blind fashion, all subjects were randomly assigned into one either a placebo (PL - 16.5 g dextrose powder per packet; n = 18) or beta-alanine (BA - 1.5 g beta-alanine plus 15 g dextrose powder per packet; n = 18) group. All subjects supplemented four times per day (total of 6 g/day) for the first 21-days, followed by two times per day (3 g/day) for the subsequent 21 days, and engaged in a total of six weeks of HIIT training consisting of 5-6 bouts of a 2:1 minute cycling work to rest ratio. RESULTS: Significant improvements in VO2peak, VO2TTE, and TWD after three weeks of training were displayed (p<0.05). Increases in VO2peak, VO2TTE, TWD and lean body mass were only significant for the BA group after the second three weeks of training. CONCLUSION: The use of HIIT to induce significant aerobic improvements is effective and efficient. Chronic BA supplementation may further enhance HIIT, improving endurance performance and lean body mass. Article Published Date : Jan 01, 2009

A low-fat diet and/or strenuous exercise alters the IGF axis in vivo and reduces prostate tumor cell growth in vitro.

Abstract Title: A low-fat diet and/or strenuous exercise alters the IGF axis in vivo and reduces prostate tumor cell growth in vitro. Abstract Source: Prostate. 2003 Aug 1;56(3):201-6. PMID: 12772189 Abstract Author(s): R James Barnard, Tung H Ngo, Pak-Shan Leung, William J Aronson, Lawrence A Golding Abstract: BACKGROUND: Prostate cancer is the most common solid-tumor cancer in US males but is rare in Asian males. When Asian men adopt the US lifestyle, clinical prostate cancer increases greatly. Epidemiological data from men in the US indicate that regular activity may reduce the risk for prostate cancer. METHODS: Serum was obtained from three groups of similar-aged men, Control, Diet and Exercise, and Exercise alone were used to stimulate LNCaP cells in culture. Growth and apoptosis of tumor cells were measured. Serum samples were also used to measure insulin, IGF-1, IGFBP-1. RESULTS: The Diet and Exercise and the Exercise alone groups had lower serum insulin and IGF-1 but higher IGFBP-1 compared to Controls. LNCaP cell growth was reduced in both groups compared to Control and there was a major increase in apoptosis of tumor cells. CONCLUSIONS: A low-fat diet and/or intensive exercise results in change in serum hormones and growth factors in vivo that can reduce growth and induce apoptosis of LNCaP prostate tumor cells in vitro. Copyright 2003 Wiley-Liss, Inc. Article Published Date : Aug 01, 2003
Therapeutic Actions EXERCISE Strenuous

NCBI pubmed

No pain, no gain? Recovery and strenuousness of physical activity.

Related Articles No pain, no gain? Recovery and strenuousness of physical activity. J Occup Health Psychol. 2018 Dec 17;: Authors: van Hooff MLM, Benthem de Grave RM, Geurts SAE Abstract The present study aimed to advance insight in the role of leisure time physical activity (LTPA) in the recovery process, by focusing on the strenuousness of LTPA. It was proposed that-compared with less strenuous LTPA-more strenuous LTPA would show stronger positive relationships with recovery through higher levels of mental disengagement from stressors resulting from more strenuous LTPA. This hypothesis was examined in two studies, in which participants' positive and negative affective states were included as indicators of recovery. Study 1 was a 10-day daily diary study (3 measurements daily) among 74 employees. Each day, participants reported the time they had spent on mild, moderate, and strenuous LTPA. Multilevel path analysis showed that only strenuous LTPA was related to beneficial changes in the two indicators of recovery before bedtime and in the next morning through its positive relationship with psychological detachment from work. Study 2 was an experiment with two between-participants conditions, in which-after a stress-inducing task-44 participants engaged in either (a) a 20-min moderate intensity cycling task, or (b) a 20-min high intensity cycling task. Results showed that high intensity exercise was indirectly related to higher recovery as indicated by a lower level of participants' negative affective state, through lower levels of rumination about the stress-inducing task in this condition. The results of these two studies indicate that to fully savor LTPA's beneficial effects through mental disengagement from stressors, it is best conducted with a high level of strenuousness. (PsycINFO Database Record (c) 2018 APA, all rights reserved). PMID: 30556711 [PubMed - as supplied by publisher]
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