CYBERMED LIFE - ORGANIC  & NATURAL LIVING

Stress

  • A new paradigm for depression in new mothers: the central role of inflammation and how breastfeeding and anti-inflammatory treatments protect maternal mental health📎

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    Abstract Title:

    A new paradigm for depression in new mothers: the central role of inflammation and how breastfeeding and anti-inflammatory treatments protect maternal mental health.

    Abstract Source:

    Int Breastfeed J. 2007;2:6. Epub 2007 Mar 30. PMID: 17397549

    Abstract Author(s):

    Kathleen Kendall-Tackett

    Abstract:

    BACKGROUND: Research in the field of psychoneuroimmunology (PNI) has revealed that depression is associated with inflammation manifested by increased levels of proinflammatory cytokines. DISCUSSION: The old paradigm described inflammation as simply one of many risk factors for depression. The new paradigm is based on more recent research that has indicated that physical and psychological stressors increase inflammation. These recent studies constitute an important shift in the depression paradigm: inflammation is not simply a risk factor; it is the risk factor that underlies all the others. Moreover, inflammation explains why psychosocial, behavioral and physical risk factors increase the risk of depression. This is true for depression in general and for postpartum depression in particular. Puerperal women are especially vulnerable to these effects because their levels of proinflammatory cytokines significantly increase during the last trimester of pregnancy--a time when they are also at high risk for depression. Moreover, common experiences of new motherhood, such as sleep disturbance, postpartum pain, and past or current psychological trauma, act as stressors that cause proinflammatory cytokine levels to rise. Breastfeeding has a protective effect on maternal mental health because it attenuates stress and modulates the inflammatory response. However, breastfeeding difficulties, such as nipple pain, can increase the risk of depression and must be addressed promptly. CONCLUSION: PNI research suggests two goals for the prevention and treatment of postpartum depression: reducing maternal stress and reducing inflammation. Breastfeeding and exercise reduce maternal stress and are protective of maternal mood. In addition, most current treatments for depression are anti-inflammatory. These include long-chain omega-3 fatty acids, cognitive therapy, St. John's wort, and conventional antidepressants.

  • A randomized controlled trial of high dose ascorbic acid for reduction of blood pressure, cortisol, and subjective responses to psychological stress.

    Abstract Title:

    A randomized controlled trial of high dose ascorbic acid for reduction of blood pressure, cortisol, and subjective responses to psychological stress.

    Abstract Source:

    Psychopharmacology (Berl). 2002 Jan;159(3):319-24. Epub 2001 Nov 20. PMID: 11862365

    Abstract Author(s):

    Stuart Brody, Ragnar Preut, Kerstin Schommer, Thomas H Schürmeyer

    Abstract:

    RATIONALE: Physiological responses to stress are considered disruptive to health. High-dose ascorbic acid has reduced indices of stress in laboratory animals. METHODS: We conducted a randomized double-blind, placebo-controlled 14-day trial of sustained-release ascorbic acid (60 healthy young adults; 3 x1000 mg/day Cetebe) and placebo (60 healthy young adults) for reduction of blood pressure, cortisol, and subjective response to acute psychological stress (Trier Social Stress Test, TSST, consisting of public speaking and mental arithmetic). Six subjects from each group were excluded. RESULTS: Compared to the placebo group, the ascorbic acid group had less systolic blood pressure (an increase of 23 versus 31 mmHg), diastolic blood pressure, and subjective stress responses to the TSST; and also had faster salivary cortisol recovery (but not smaller overall cortisol response). Cortisol response to 1 microg ACTH, and reported side-effects during the trial did not differ between groups. Plasma ascorbic acid level at the end of the trial but not pre-trial was associated with reduced stress reactivity of systolic blood pressure, diastolic blood pressure, and subjective stress, and with greater salivary cortisol recovery. CONCLUSIONS: Treatment with high-dose sustained-release ascorbic acid palliates blood pressure, cortisol, and subjective response to acute psychological stress. These effects are not attributable to modification of adrenal responsiveness.

  • Antifatigue and antistress effect of the hot-water fraction from mycelia of Cordyceps sinensis📎

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    Abstract Title:

    Antifatigue and antistress effect of the hot-water fraction from mycelia of Cordyceps sinensis.

    Abstract Source:

    Biol Pharm Bull. 2003 May;26(5):691-4. PMID: 12736514

    Abstract Author(s):

    Jong-Ho Koh, Kyung-Mi Kim, Jin-Man Kim, Jae-Chul Song, Hyung-Joo Suh

    Abstract:

    This study was conducted to investigate the chemical component of the hot water (HW) fraction of mycelia of Cordyceps sinensis and its antifatigue and antistress effect against a stimulus in vivo using rats and mice. The growth of mycelia reached a maximum level of 31.6 g/l after 120 h of incubation. The main chemical composition of the HW fraction of mycelia of C. sinensis was found to be carbohydrate (78.9%) with 5% moisture. The swimming endurance capacity of mice orally administered with the HW fraction (150 and 300 mg/kg/d, respectively) was significantly prolonged from 75 to 90 min with a lessening of fatigue. When the HW fraction (150 mg/kg/d) was given to rats for 8 d including a 48 h stress period, the weight changes of the adrenal gland, spleen, thymus, and thyroid, which is an index of stress, were suppressed. The HW fraction also significantly inhibited the increase in total cholesterol and the decrease in alkaline phosphatase levels as biochemical parameters of immobilization stress in rats.

  • Antistress and antioxidant effects of virgin coconut oil in vivo📎

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    Abstract Title:

    Antistress and antioxidant effects of virgin coconut oil in vivo.

    Abstract Source:

    Exp Ther Med. 2015 Jan ;9(1):39-42. Epub 2014 Nov 3. PMID: 25452773

    Abstract Author(s):

    Swee Keong Yeap, Boon Kee Beh, Norlaily Mohd Ali, Hamidah Mohd Yusof, Wan Yong Ho, Soo Peng Koh, Noorjahan Banu Alitheen, Kamariah Long

    Article Affiliation:

    Swee Keong Yeap

    Abstract:

    Virgin coconut oil (VCO) has been consumed worldwide for various health-related reasons and some of its benefits have been scientifically evaluated. Medium-chain fatty acids were found to be a potential antidepressant functional food; however, this effect had not been evaluated in VCO, which is rich in polyphenols and medium-chain fatty acids. The aim of this study was to evaluate the antistress and antioxidant effects of VCO in vivo, using mice with stress-induced injury. The antistress effect of VCO (administered per os, at a dose of 10 ml/kg body weight) was evaluated using the forced swim test and chronic cold restraint stress models. VCO was able to reduce immobility time and restore oxidative stress in mice post-swim test. Furthermore, mice treated with VCO were found to exhibit higher levels of brain antioxidants, lower levels of brain 5-hydroxytryptamine and reduced weight of the adrenal glands. Consequently, the serum cholesterol, triglyceride, glucose and corticosterone levels were also lower in VCO-treated mice. These results suggest the potential value of VCO as an antistress functional oil.

  • Beneficial effects of treatment with sensory isolation in flotation-tank as a preventive health-care intervention - a randomized controlled pilot trial. 📎

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    Abstract Title:

    Beneficial effects of treatment with sensory isolation in flotation-tank as a preventive health-care intervention - a randomized controlled pilot trial.

    Abstract Source:

    BMC Complement Altern Med. 2014 ;14:417. Epub 2014 Oct 25. PMID: 25344737

    Abstract Author(s):

    Anette Kjellgren, Jessica Westman

    Article Affiliation:

    Anette Kjellgren

    Abstract:

    BACKGROUND:Sensory isolation in a flotation tank is a method known for inducing deep relaxation and subsequent positive health effects for patients suffering from e.g. stress or muscle tensions pains. Very few studies have investigated this method as a preventive health-care intervention. The purpose of this study was to evaluate the effects in healthy participants after receiving a series of flotation tank treatment.

    METHODS:Sixty-five participants (14 men and 51 women) who were all part of a cooperative-health project initiated by their individual companies, were randomized to either a wait-list control group or a flotation tank treatment group where they participated in a seven weeks flotation program with a total of twelve flotation sessions. Questionnaires measuring psychological and physiological variables such as stress and energy, depression and anxiety, optimism, pain, stress, sleep quality, mindfulness, and degree of altered states of consciousness were used. Data were analysed by two-way mixed MANOVA and repeated measures ANOVA.

    RESULTS:Stress, depression, anxiety, and worst pain were significantly decreased whereas optimism and sleep quality significantly increased for the flotation-REST group. No significant results for the control group were seen. There was also a significant correlation between mindfulness in daily life and degree of altered states of consciousness during the relaxation in the flotation tank.

    CONCLUSIONS:It was concluded that flotation-REST has beneficial effects on relatively healthy participants.

    TRIAL REGISTRATION:Australian New Zealand Clinical Trials Registry: ACTRN12613000483752.

  • Beneficial effects of treatment with sensory isolation in flotation-tank as a preventive health-care intervention - a randomized controlled pilot trial. 📎

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    Abstract Title:

    Beneficial effects of treatment with sensory isolation in flotation-tank as a preventive health-care intervention - a randomized controlled pilot trial.

    Abstract Source:

    BMC Complement Altern Med. 2014 ;14:417. Epub 2014 Oct 25. PMID: 25344737

    Abstract Author(s):

    Anette Kjellgren, Jessica Westman

    Article Affiliation:

    Anette Kjellgren

    Abstract:

    BACKGROUND:Sensory isolation in a flotation tank is a method known for inducing deep relaxation and subsequent positive health effects for patients suffering from e.g. stress or muscle tensions pains. Very few studies have investigated this method as a preventive health-care intervention. The purpose of this study was to evaluate the effects in healthy participants after receiving a series of flotation tank treatment.

    METHODS:Sixty-five participants (14 men and 51 women) who were all part of a cooperative-health project initiated by their individual companies, were randomized to either a wait-list control group or a flotation tank treatment group where they participated in a seven weeks flotation program with a total of twelve flotation sessions. Questionnaires measuring psychological and physiological variables such as stress and energy, depression and anxiety, optimism, pain, stress, sleep quality, mindfulness, and degree of altered states of consciousness were used. Data were analysed by two-way mixed MANOVA and repeated measures ANOVA.

    RESULTS:Stress, depression, anxiety, and worst pain were significantly decreased whereas optimism and sleep quality significantly increased for the flotation-REST group. No significant results for the control group were seen. There was also a significant correlation between mindfulness in daily life and degree of altered states of consciousness during the relaxation in the flotation tank.

    CONCLUSIONS:It was concluded that flotation-REST has beneficial effects on relatively healthy participants.

    TRIAL REGISTRATION:Australian New Zealand Clinical Trials Registry: ACTRN12613000483752.

  • Breath-based meditation: A mechanism to restore the physiological and cognitive reserves for optimal human performance. 📎

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    Abstract Title:

    Breath-based meditation: A mechanism to restore the physiological and cognitive reserves for optimal human performance.

    Abstract Source:

    World J Clin Cases. 2016 Apr 16 ;4(4):99-102. PMID: 27099859

    Abstract Author(s):

    Kirtigandha Salwe Carter, Robert Carter

    Article Affiliation:

    Kirtigandha Salwe Carter

    Abstract:

    Stress can be associated with many physiological changes resulting in significant decrements in human performance. Due to growing interests in alternative and complementary medicine by Westerners, many of the traditions and holistic yogic breathing practices today are being utilized as a measure for healthier lifestyles. These state-of-the-art practices can have a significant impact on common mental health conditions such as depression and generalized anxiety disorder. However, the potential of yogic breathing on optimizing human performance and overall well-being is not well known. Breathing techniques such as alternate nostril, Sudarshan Kriya and bhastrika utilizes rhythmic breathing to guide practitioners into a deep meditative state of relaxation and promote self-awareness. Furthermore, yogic breathing is physiologically stimulating and can be described as a natural"technological"solution to optimize human performance which can be categorized into: (1) cognitive function (i.e., mind, vigilance); and (2) physical performance (i.e., cardiorespiratory, metabolism, exercise, whole body). Based on previous studies, we postulate that daily practice of breathing meditation techniques play a significant role in preserving the compensatory mechanisms available to sustain physiological function. This preservation of physiological function may help to offset the time associated with reaching a threshold for clinical expression of chronic state (i.e., hypertension, depression, dementia) or acute state (i.e., massive hemorrhage, panic attic) of medical conditions. However, additional rigorous biomedical research is needed to evaluate the physiological mechanisms of various forms of meditation (i.e., breath-based, mantra, mindfulness) on human performance. These efforts will help to define how compensatory reserve mechanisms of cardiovascular and immune systems are modulated by breath-based meditation. While it has been suggested that breath-based meditation is easier for beginning practitioners when compared to other forms of meditation more research is needed to elucidate these observations. A breath-based meditation sequence such as Sudarshan Kriya has the potential to help develop an individual's self-awareness and support better integration of the brain (i.e., mind) with other organ systems (i.e., body) for enhanced human performance.

  • Breath-based meditation: A mechanism to restore the physiological and cognitive reserves for optimal human performance. 📎

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    Abstract Title:

    Breath-based meditation: A mechanism to restore the physiological and cognitive reserves for optimal human performance.

    Abstract Source:

    World J Clin Cases. 2016 Apr 16 ;4(4):99-102. PMID: 27099859

    Abstract Author(s):

    Kirtigandha Salwe Carter, Robert Carter

    Article Affiliation:

    Kirtigandha Salwe Carter

    Abstract:

    Stress can be associated with many physiological changes resulting in significant decrements in human performance. Due to growing interests in alternative and complementary medicine by Westerners, many of the traditions and holistic yogic breathing practices today are being utilized as a measure for healthier lifestyles. These state-of-the-art practices can have a significant impact on common mental health conditions such as depression and generalized anxiety disorder. However, the potential of yogic breathing on optimizing human performance and overall well-being is not well known. Breathing techniques such as alternate nostril, Sudarshan Kriya and bhastrika utilizes rhythmic breathing to guide practitioners into a deep meditative state of relaxation and promote self-awareness. Furthermore, yogic breathing is physiologically stimulating and can be described as a natural"technological"solution to optimize human performance which can be categorized into: (1) cognitive function (i.e., mind, vigilance); and (2) physical performance (i.e., cardiorespiratory, metabolism, exercise, whole body). Based on previous studies, we postulate that daily practice of breathing meditation techniques play a significant role in preserving the compensatory mechanisms available to sustain physiological function. This preservation of physiological function may help to offset the time associated with reaching a threshold for clinical expression of chronic state (i.e., hypertension, depression, dementia) or acute state (i.e., massive hemorrhage, panic attic) of medical conditions. However, additional rigorous biomedical research is needed to evaluate the physiological mechanisms of various forms of meditation (i.e., breath-based, mantra, mindfulness) on human performance. These efforts will help to define how compensatory reserve mechanisms of cardiovascular and immune systems are modulated by breath-based meditation. While it has been suggested that breath-based meditation is easier for beginning practitioners when compared to other forms of meditation more research is needed to elucidate these observations. A breath-based meditation sequence such as Sudarshan Kriya has the potential to help develop an individual's self-awareness and support better integration of the brain (i.e., mind) with other organ systems (i.e., body) for enhanced human performance.

  • Breath-based meditation: A mechanism to restore the physiological and cognitive reserves for optimal human performance. 📎

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    Abstract Title:

    Breath-based meditation: A mechanism to restore the physiological and cognitive reserves for optimal human performance.

    Abstract Source:

    World J Clin Cases. 2016 Apr 16 ;4(4):99-102. PMID: 27099859

    Abstract Author(s):

    Kirtigandha Salwe Carter, Robert Carter

    Article Affiliation:

    Kirtigandha Salwe Carter

    Abstract:

    Stress can be associated with many physiological changes resulting in significant decrements in human performance. Due to growing interests in alternative and complementary medicine by Westerners, many of the traditions and holistic yogic breathing practices today are being utilized as a measure for healthier lifestyles. These state-of-the-art practices can have a significant impact on common mental health conditions such as depression and generalized anxiety disorder. However, the potential of yogic breathing on optimizing human performance and overall well-being is not well known. Breathing techniques such as alternate nostril, Sudarshan Kriya and bhastrika utilizes rhythmic breathing to guide practitioners into a deep meditative state of relaxation and promote self-awareness. Furthermore, yogic breathing is physiologically stimulating and can be described as a natural"technological"solution to optimize human performance which can be categorized into: (1) cognitive function (i.e., mind, vigilance); and (2) physical performance (i.e., cardiorespiratory, metabolism, exercise, whole body). Based on previous studies, we postulate that daily practice of breathing meditation techniques play a significant role in preserving the compensatory mechanisms available to sustain physiological function. This preservation of physiological function may help to offset the time associated with reaching a threshold for clinical expression of chronic state (i.e., hypertension, depression, dementia) or acute state (i.e., massive hemorrhage, panic attic) of medical conditions. However, additional rigorous biomedical research is needed to evaluate the physiological mechanisms of various forms of meditation (i.e., breath-based, mantra, mindfulness) on human performance. These efforts will help to define how compensatory reserve mechanisms of cardiovascular and immune systems are modulated by breath-based meditation. While it has been suggested that breath-based meditation is easier for beginning practitioners when compared to other forms of meditation more research is needed to elucidate these observations. A breath-based meditation sequence such as Sudarshan Kriya has the potential to help develop an individual's self-awareness and support better integration of the brain (i.e., mind) with other organ systems (i.e., body) for enhanced human performance.

  • Change in salivary physiological stress markers by spa bathing. 📎

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    Abstract Title:

    Change in salivary physiological stress markers by spa bathing.

    Abstract Source:

    Biomed Res. 2006 Feb;27(1):11-4. PMID: 16543660

    Abstract Author(s):

    Masahiro Toda, Kanehisa Morimoto, Shingo Nagasawa, Kazuyuki Kitamura

    Abstract:

    We assessed the stress relief effect of spa bathing by measuring sensitive salivary stress markers, cortisol and chromogranin A (CgA). From 12 healthy males, saliva samples were collected immediately before and after spa bathing, and 30 min after that. Salivary cortisol and CgA levels were determined by ELISA. Salivary cortisol levels decreased after spa bathing. This tendency was more pronounced in individuals with higher levels of stress. The high-stress group showed lower salivary CgA levels after spa bathing, while the low-stress group higher salivary CgA levels in the same condition. These findings suggest that the spa bathing has a moderate affect on the stress relief.

  • Chewing gum alleviates negative mood and reduces cortisol during acute laboratory psychological stress.

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    Abstract Title:

    Chewing gum alleviates negative mood and reduces cortisol during acute laboratory psychological stress.

    Abstract Source:

    Physiol Behav. 2009 Jun 22;97(3-4):304-12. Epub 2009 Mar 5. PMID: 19268676

    Abstract Author(s):

    Andrew Scholey, Crystal Haskell, Bernadette Robertson, David Kennedy, Anthea Milne, Mark Wetherell

    Abstract:

    The notion that chewing gum may relieve stress was investigated in a controlled setting. A multi-tasking framework which reliably evokes stress and also includes performance measures was used to induce acute stress in the laboratory. Using a randomised crossover design forty participants (mean age 21.98 years) performed on the multi-tasking framework at two intensities (on separate days) both while chewing and not chewing. Order of workload intensity and chewing conditions were counterbalanced. Before and after undergoing the platform participants completed the state portion of the State-Trait Anxiety Inventory, Bond-Lader visual analogue mood scales, a single Stress Visual Analogue Scale and provided saliva samples for cortisol measurement. Baseline measures showed that both levels of the multi-tasking framework were effective in significantly reducing self-rated alertness, calmness and contentment while increasing self-rated stress and state anxiety. Cortisol levels fell during both levels of the stressor during the morning, reflecting the predominance of a.m. diurnal changes, but this effect was reversed in the afternoon which may reflect a measurable stress response. Pre-post stressor changes (Delta) for each measure at baseline were subtracted from Delta scores under chewing and no chewing conditions. During both levels of stress the chewing gum condition was associated with significantly better alertness and reduced state anxiety, stress and salivary cortisol. Overall performance on the framework was also significantly better in the chewing condition. The mechanisms underlying these effects are unknown but may involve improved cerebral blood flow and/or effects secondary to performance improvement during gum chewing.

  • Coconut fragrance and cardiovascular response to laboratory stress: results of pilot testing.

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    Abstract Title:

    Coconut fragrance and cardiovascular response to laboratory stress: results of pilot testing.

    Abstract Source:

    Holist Nurs Pract. 2010 Nov-Dec;24(6):322-32. PMID: 21037456

    Abstract Author(s):

    Elizabeth Sibolboro Mezzacappa, Uma Arumugam, Sylvia Yue Chen, Traci R Stein, Mehmet Oz, Jane Buckle

    Article Affiliation:

    Elizabeth Sibolboro Mezzacappa

    Abstract:

    There is preliminary evidence that pleasant fragrances may alter response to stressors in different settings. This pilot study examined the effect of coconut fragrance on cardiovascular response to standard laboratory stressors. While inhaling coconut fragrance (n = 17) or air (n = 15), subjects performed a Stroop color-word task and a mental arithmetic task. Heart rate (HR), heart period variability (HPV) and blood pressure were measured during the 5-minute baseline, the task, and the recovery periods. The results indicated that subjects breathing coconut fragrance had higher HR and lower HPV than those who performed tasks while breathing air. HR response to mental arithmetic seemed to be blunted in the subjects breathing coconut; however, the lack of a difference in HPV seems to indicate that the blunting may be due to decreased sympathetic response, not decreased parasympathetic withdrawal under stress. Blood pressure recovery was slightly enhanced in subjects under coconut fragrance. Thus, the results of this pilot test suggest that coconut fragrance may alter cardiovascular activity both at rest and in response to stressors. Future experimentation should attempt to replicate and extend these findings in larger samples in clinical settings.

  • Composite effects of group drumming music therapy on modulation of neuroendocrine-immune parameters in normal subjects.

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    Abstract Title:

    Composite effects of group drumming music therapy on modulation of neuroendocrine-immune parameters in normal subjects.

    Abstract Source:

    Altern Ther Health Med. 2001 Jan;7(1):38-47. PMID: 11191041

    Abstract Author(s):

    B B Bittman, L S Berk, D L Felten, J Westengard, O C Simonton, J Pappas, M Ninehouser

    Abstract:

    CONTEXT: Drum circles have been part of healing rituals in many cultures throughout the world since antiquity. Although drum circles are gaining increased interest as a complementary therapeutic strategy in the traditional medical arena, limited scientific data documenting biological benefits associated with percussion activities exist.

    OBJECTIVE: To determine the role of group-drumming music therapy as a composite activity with potential for alteration of stress-related hormones and enhancement of specific immunologic measures associated with natural killer cell activity and cell-mediated immunity.

    DESIGN: A single trial experimental intervention with control groups.

    SETTING: The Mind-Body Wellness Center, an outpatient medical facility in Meadville, Pa.

    PARTICIPANTS: A total of 111 age- and sex-matched volunteer subjects (55 men and 56 women, with a mean age of 30.4 years) were recruited.

    INTERVENTION: Six preliminary supervised groups were studied using various control and experimental paradigms designed to separate drumming components for the ultimate determination of a single experimental model, including 2 control groups (resting and listening) as well as 4 group-drumming experimental models (basic, impact, shamanic, and composite). The composite drumming group using a music therapy protocol was selected based on preliminary statistical analysis, which demonstrated immune modulation in a direction opposite to that expected with the classical stress response. The final experimental design included the original composite drumming group plus 50 additional age- and sex-matched volunteer subjects who were randomly assigned to participate in group drumming or control sessions.

    MAIN OUTCOME MEASURES: Pre- and postintervention measurements of plasma cortisol, plasma dehydroepiandrosterone, plasma dehydroepiandrosterone-to-cortisol ratio, natural killer cell activity, lymphokine-activated killer cell activity, plasma interleukin-2, plasma interferon-gamma, the Beck Anxiety Inventory, and the Beck Depression Inventory II.

    RESULTS: Group drumming resulted in increased dehydroepiandrosterone-to-cortisol ratios, increased natural killer cell activity, and increased lymphokine-activated killer cell activity without alteration in plasma interleukin 2 or interferon-gamma, or in the Beck Anxiety Inventory and the Beck Depression Inventory II.

    CONCLUSIONS: Drumming is a complex composite intervention with the potential to modulate specific neuroendocrine and neuroimmune parameters in a direction opposite to that expected with the classic stress response.

  • Diaphragmatic Breathing Reduces Exercise-induced Oxidative Stress. 📎

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    Abstract Title:

    Diaphragmatic Breathing Reduces Exercise-induced Oxidative Stress.

    Abstract Source:

    Evid Based Complement Alternat Med. 2009 Oct 29. PMID: 19875429

    Abstract Author(s):

    Daniele Martarelli, Mario Cocchioni, Stefania Scuri, Pierluigi Pompei

    Abstract:

    Diaphragmatic breathing is relaxing and therapeutic, reduces stress, and is a fundamental procedure of Pranayama Yoga, Zen, transcendental meditation and other meditation practices. Analysis of oxidative stress levels in people who meditate indicated that meditation correlates with lower oxidative stress levels, lower cortisol levels and higher melatonin levels. It is known that cortisol inhibits enzymes responsible for the antioxidant activity of cells and that melatonin is a strong antioxidant; therefore, in this study, we investigated the effects of diaphragmatic breathing on exercise-induced oxidative stress and the putative role of cortisol and melatonin hormones in this stress pathway. We monitored 16 athletes during an exhaustive training session. After the exercise, athletes were divided in two equivalent groups of eight subjects. Subjects of the studied group spent 1 h relaxing performing diaphragmatic breathing and concentrating on their breath in a quiet place. The other eight subjects, representing the control group, spent the same time sitting in an equivalent quite place. Results demonstrate that relaxation induced by diaphragmatic breathing increases the antioxidant defense status in athletes after exhaustive exercise. These effects correlate with the concomitant decrease in cortisol and the increase in melatonin. The consequence is a lower level of oxidative stress, which suggests that an appropriate diaphragmatic breathing could protect athletes from long-term adverse effects of free radicals.

  • Effect of controlled breathing exercises on the psychological status and the cardiac autonomic tone: Sudarshan Kriya and Prana-Yoga.

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    Abstract Title:

    Effect of controlled breathing exercises on the psychological status and the cardiac autonomic tone: Sudarshan Kriya and Prana-Yoga.

    Abstract Source:

    Indian J Physiol Pharmacol. 2014 Jul-Sep;58(3):211-21. PMID: 25906603

    Abstract Author(s):

    Chhaya Kharya, Varun Gupta, Kishore Kumar Deepak, Rajesh Sagar, Ashish Upadhyav, Vinod Kochupillai, Sneh Anand

    Article Affiliation:

    Chhaya Kharya

    Abstract:

    OBJECTIVE:The objective of the study was to observe the effect of controlled breathing exercises including Sudarshan Kriya (SK) and Prana-Yoga (PY) on the psycho-physiological status.

    METHODS:The study group included 60 healthy volunteers (M:30, F:30) in the age group of 18 to 30 years (21.3± 3.2 yrs), randomly divided in to three groups of 20 subjects each--(1) The SK group (2) the PY group and the (3) Control group. The psycho-physiological data was collected at the following four time interventions: Baseline, 6th, 60th and the 150th day. Psychological assessment was done using questionnaires and for the autonomic tone quantification Heart Rate Variability (HRV) analysis was done using the standard lead II electrocardiogram recordings. In a post-hoc analysis each group was further sub divided in to the following two patterns, based on the baseline values of normalized Low Frequency (LF) power (cutoff 64 ms2): (i) Pattern A-Subjects with low level LF power, and (ii) Pattern B- subjects with high level LF power.

    RESULTS:The stress management skills have shown significant increase in SK group but not in PY and Control group. Subjects of SK, PY, and control group showed significant increase in LF value and LF:HF ratio for pattern A and significant decrease for pattern B. Plotted LF value for pattern A&B in SK and PY practitioners showed convergence, coming to a mean value over the period of 150 days. The LF:HF ratio curve plotted over time for pattern A&B showed convergence in SK group only. No such convergence in LF value&LF/HF ratio for pattern A&B was seen in control group.

    CONCLUSION:In conclusion, Sudarshan Kriya positively modifies stress coping behavior and initiates appropriate balance in cardiac autonomic tone.

  • Effect of controlled breathing exercises on the psychological status and the cardiac autonomic tone: Sudarshan Kriya and Prana-Yoga.

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    Abstract Title:

    Effect of controlled breathing exercises on the psychological status and the cardiac autonomic tone: Sudarshan Kriya and Prana-Yoga.

    Abstract Source:

    Indian J Physiol Pharmacol. 2014 Jul-Sep;58(3):211-21. PMID: 25906603

    Abstract Author(s):

    Chhaya Kharya, Varun Gupta, Kishore Kumar Deepak, Rajesh Sagar, Ashish Upadhyav, Vinod Kochupillai, Sneh Anand

    Article Affiliation:

    Chhaya Kharya

    Abstract:

    OBJECTIVE:The objective of the study was to observe the effect of controlled breathing exercises including Sudarshan Kriya (SK) and Prana-Yoga (PY) on the psycho-physiological status.

    METHODS:The study group included 60 healthy volunteers (M:30, F:30) in the age group of 18 to 30 years (21.3± 3.2 yrs), randomly divided in to three groups of 20 subjects each--(1) The SK group (2) the PY group and the (3) Control group. The psycho-physiological data was collected at the following four time interventions: Baseline, 6th, 60th and the 150th day. Psychological assessment was done using questionnaires and for the autonomic tone quantification Heart Rate Variability (HRV) analysis was done using the standard lead II electrocardiogram recordings. In a post-hoc analysis each group was further sub divided in to the following two patterns, based on the baseline values of normalized Low Frequency (LF) power (cutoff 64 ms2): (i) Pattern A-Subjects with low level LF power, and (ii) Pattern B- subjects with high level LF power.

    RESULTS:The stress management skills have shown significant increase in SK group but not in PY and Control group. Subjects of SK, PY, and control group showed significant increase in LF value and LF:HF ratio for pattern A and significant decrease for pattern B. Plotted LF value for pattern A&B in SK and PY practitioners showed convergence, coming to a mean value over the period of 150 days. The LF:HF ratio curve plotted over time for pattern A&B showed convergence in SK group only. No such convergence in LF value&LF/HF ratio for pattern A&B was seen in control group.

    CONCLUSION:In conclusion, Sudarshan Kriya positively modifies stress coping behavior and initiates appropriate balance in cardiac autonomic tone.

  • Effect of lavender aroma on salivary endocrinological stress markers.

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    Abstract Title:

    Effect of lavender aroma on salivary endocrinological stress markers.

    Abstract Source:

    Arch Oral Biol. 2008 Oct;53(10):964-8. Epub 2008 Jul 16. PMID: 18635155

    Abstract Author(s):

    Masahiro Toda, Kanehisa Morimoto

    Abstract:

    OBJECTIVE: We evaluated the stress relief effect of lavender aroma by measuring sensitive salivary endocrinological stress markers, cortisol and chromogranin A (CgA). DESIGN: Thirty healthy students performed a serial arithmetic task for 10min and then rested for 10min. During the resting period, 16 students (aroma group) were exposed to airborne organic essential oil of lavender. Saliva samples were collected immediately before and after the arithmetic task, and at 5 and 10min after that. Salivary cortisol and CgA levels were determined by enzyme-linked immunosorbent assay. RESULTS: In the aroma group, levels of CgA that had been elevated at the end of the arithmetic task were statistically significantly lower 10min later. The control group showed no such change. During the protocol, no statistically significant changes in levels of cortisol were detected in either the aroma group or the control group. CONCLUSIONS: These findings suggest that lavender aroma has a stress relief effect.

  • Effects of Electroacupuncture on Chronic Unpredictable Mild Stress Rats Depression-Like Behavior and Expression of p-ERK/ERK and p-P38/P38. 📎

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    Abstract Title:

    Effects of Electroacupuncture on Chronic Unpredictable Mild Stress Rats Depression-Like Behavior and Expression of p-ERK/ERK and p-P38/P38.

    Abstract Source:

    Evid Based Complement Alternat Med. 2015 ;2015:650729. Epub 2015 Aug 20. PMID: 26366182

    Abstract Author(s):

    Jian Xu, Yanling She, Ning Su, Ruixin Zhang, Lixing Lao, Shifen Xu

    Article Affiliation:

    Jian Xu

    Abstract:

    We investigate the antidepressant-like effect and mechanism of electroacupuncture (EA) on a chronic unpredictable mild stress rats depression-like behavior. In our study, depression in rats was induced by unpredictable chronic mild stress (UCMS) and isolation for four weeks. Male Sprague-Dawley rats were randomly divided into four groups: Normal, Model, EA, and Sham EA. EA treatment was administered for two weeks, once a day for five days a week. Two acupoints, Yintang (EX-HN3) and Baihui (GV20), were selected. For sham EA, acupuncture needles were inserted shallowly into the acupoints: EX-HN3 and GV20. No electrostimulator was connected. The antidepressant-like effect of the electroacupuncture treatment was measured by sucrose intake test, open field test, and forced swimming test in rats. The protein levels of phosphorylated extracellular regulated protein kinases (p-ERK1/2)/ERK1/2 and p-P38/P38 in the hippocampus (HP) were examined by Western blot analysis. Our data demonstrate that EA treatment decreased the immobility time of forced swimming test and improved the sucrose solution intake in comparison to unpredictable chronic mild stress and placebo sham control. Electroacupuncture may act on depression by enhancing p-ERK1/2 and p-p38 in the hippocampus.

  • Effects of external qi-therapy on emotions, electroencephalograms, and plasma cortisol.

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    Abstract Title:

    Effects of external qi-therapy on emotions, electroencephalograms, and plasma cortisol.

    Abstract Source:

    Int J Neurosci. 2004 Nov;114(11):1493-502. PMID: 15636358

    Abstract Author(s):

    Myeong Soo Lee, Young Hoon Rim, Chang-Won Kang

    Abstract:

    The authors investigated the effect of external Qi-therapy (EQT) on changes in encephalograms (EEGs) and circulating cortisol concentrations. Ten college students participated in crossover sessions, receiving EQT or placebo treatment with their eyes open. Subjects reported improved emotions of satisfaction, relaxation, and calmness during EQT as compared to levels reported during placebo treatments. There were significant differences in the proportions of alpha and beta EEG waves between the two sessions, and the relative strengths of alpha waves were higher during EQT than during control sessions (p<.05). Plasma cortisol concentrations during EQT were significantly lower than during control sessions p<.05). Thus, Qi-therapy was more effective in inducing relaxation than placebo treatment.

  • Effects of Hatha yoga and African dance on perceived stress, affect, and salivary cortisol.

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    Abstract Title:

    Effects of Hatha yoga and African dance on perceived stress, affect, and salivary cortisol.

    Abstract Source:

    J Vasc Surg. 2001 Sep;34(3):474-81. PMID: 15454358

    Abstract Author(s):

    Jeremy West, Christian Otte, Kathleen Geher, Joe Johnson, David C Mohr

    Abstract:

    BACKGROUND: Dance and yoga have been shown to produce improvements in psychological well-being.

    PURPOSE: The aim of this study was to examine some of the psychological and neuroendocrine response to these activities.

    METHODS: Sixty-nine healthy college students participated in one of three 90-min classes: African dance (n = 21), Hatha yoga (n= 18), or a biology lecture as a control session (n = 30). Before and after each condition participants completed the Perceived Stress Scale (PSS), completed the Positive Affect and Negative Affect Schedule, and provided a saliva sample for cortisol. RESULTS: There were significant reductions in PSS and negative affect (ps < .0001) and Time x Treatment interactions (ps < .0001) such that African dance and Hatha yoga showed significant declines, whereas there was no significant change in biology lecture. There was no significant main effect for positive affect (p = .53), however there was a significant interaction effect (p < .001) such that positive affect increased in African dance, decreased in biology lecture, and did not change significantly in Hatha yoga. There was a significant main effect for salivary cortisol (p < .05) and a significant interaction effect (p < .0001) such that cortisol increased in African dance, decreased in Hatha yoga, and did not change in biology. Changes in cortisol were not significantly related to changes in psychological variables across treatments. There was 1 significant interaction effect (p = .04) such that change in positive affect and change in cortisol were negatively correlated in Hatha yoga but positively correlated in Africa dance and biology.

    CONCLUSIONS: Both African dance and Hatha yoga reduced perceived stress and negative affect. Cortisol increased in African dance and decreased in Hatha yoga. Therefore, even when these interventions produce similar positive psychological effects, the effects may be very different on physiological stress processes. One factor that may have particular salience is that amount of physiological arousal produced by the intervention.

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